Enteric resin (L 30D-55 /L100-55)

pH-dependent controlled release excipients, insoluble in water, and low permeability. .
It can be used for sustained-release enteric coating.
Swell at pH < 5.5 and dissolve at pH > 5.5 (release in duodenum).

Chemical Name:
Methacrylic acid-ethyl acrylate copolymer (weight ratio ≈ 1:1)

中文名:
甲基丙烯酸-丙烯酸乙酯共聚物水分散体 (L30D-55 / MAE 30DP)
甲基丙烯酸共聚物 C型 (L100-55干粉规格在 CDE 曾用名)

English name:
Methacrylic Acid and Ethyl Acrylate Copolymer Dispersion (NF36)
Methacrylic Acid - Ethyl Acrylate Copolymer (1:1) Dispersion 30 Per Cent (EP9.0)

Japanese name:
メタクリル酸コポリマーLD / 乾燥メタクリル酸コポリマーLD（医薬品添加物規格）

CAS: 25212-88-8
UNII：NX76LV5T8J

Quality specification: CP、USP、EP、JPE

Physical properties
Properties: Milky white low viscosity liquid (L 30D-55) or white powder (L 100-55); slightly odor. The solids contained 0.7% sodium lauryl sulfate and 2.3% polysorbate 80.
Average molecular weight Mw: ≈320,000 g/mol;  

Tg: 96 °C.
Extensibility: Poor (10-30% plasticizer added).

Chemical properties
Anionic property, weakly acidic;
Swell at pH <5.5 , permeability; dissolve below pH > 5.5  (duodenal release).